Skin care products containing retinol and retinoids have been shown to promote collagen production and reverse some of the signs of aging. Retinol is a form of vitamin A that has been shown to improve skin elasticity when combined with vitamin C. Retinol and retinoids are found in many over-the-counter skin products and prescription drugs. Vitamins C, B3 and E are the most important antioxidants due to their ability to penetrate the skin thanks to their small molecular weight, 52 Local L-ascorbic acid (vitamin C) soluble in water and labile to heat, in concentrations of between 5 and 15%, has an anti-aging effect on the skin by inducing the production of Col-1 and Col-3, as well as enzymes important for the production of collagen and matrix metalloproteinase (MMP) 1 (collagenase) inhibitors. It works by smoothing the skin and increasing the capacity of the stratum corneum to maintain its moisture, accelerate epithelialization and contribute to skin photoprotection.
The effects are not as strong as those of vitamins C and B35. Ultherapy is a non-invasive procedure that uses microfused ultrasound waves to stimulate collagen growth in the body and tighten the skin. Intraceuticals Infusion is a gentle treatment that uses pressurized hyperbaric oxygen to infuse hyaluronic acid and antioxidant serums into the skin to volumize, rejuvenate, moisturize and replenish the skin. Taking supplements can also help increase the protein stores that the skin loses as it ages, helping the skin to become firmer and fine lines and wrinkles are less evident. Thousands of microscopic holes are made in the skin (without damaging it), causing treated skin to produce new collagen and elastin and generate new cells to heal.
One study found that the skin of people over 40 who exercised looked more like the skin of someone in their 20s when examined under a microscope. Radiesse contains calcium hydroxylapatite and is diluted with saline and lidocaine when used to stimulate collagen production and tighten the skin. Professional radio-frequency-based skin treatment devices, such as EndyMedPro 3DEEP, use several treatment methods, often combined, to stretch, tighten and illuminate the skin, stimulating fibroblasts to produce new collagen and elastin. When skin grows back, the production of new collagen is triggered, leaving skin smoother and younger looking.
The body then regenerates and repairs skin over time, working below the surface of the dermis to form new collagen, generate new skin cells, and improve blood supply. The loss of skin elasticity is officially known as elastosis, meaning the degeneration of skin tissue due to aging and other factors. It has been shown to reduce signs of UV-induced premature skin aging, such as wrinkles, loss of elasticity and skin pigmentation. Medium-depth peels, such as the PCA Peel or the Perfect Peel, combine several acids and vitamins to improve skin tone, texture, and clarity, and act at the cellular level rather than simply removing the top layer of skin.
Non-ablative skin rejuvenation is not a precise term, as rejuvenation is a controlled way of injuring the skin with the goal of achieving a more youthful appearance once the wound has healed.